golub

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Golub Data

Description

Normalized version of the Golub leukemia data from the golubEsets package, available from http://www.bioconductor.org/download/experiments/. Republished from the hddplot package by John Maindonald on 10 March 2018.

Usage

data("golub")

Format

A data frame with 72 observations on the following 6 variables and 7,129 gene probes.

Samples

a numeric vector: sample number

BM.PB

a factor with levels BM (from bone marrow) PB (from peripheral blood)

Gender

a factor with levels F (female) M (male)

Source

a factor with levels CALGB CCG DFCI St-Jude. These are the hospitals from which the samples originated.

tissue.mf

a factor with levels BM:NA BM:f BM:m PB:NA PB:f PB:m. This factor identifies the combinations of source and Gender

cancer

a factor with levels allB allT aml. There are two types of Acute Lymphoblastic Leukemia (allB and allT), plus Acute Myeloblastic Leukemia (aml)

Details

Expression data have been normalized and are supplied here in the last 7,129 columns. This dataset is a merged version of Golub and golubInfo from the hddplot package by John Maindonald.

Source

See the help page for the dataset golubMerge, in the golubEsets package, for details of the source of the original data.

References

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring, Science, 531-537, 1999. T.R. Golub and D.K. Slonim and P. Tamayo and C. Huard and M. Gaasenbeek and J.P. Mesirov and H. Coller and M.L. Loh and J.R. Downing and M.A. Caligiuri and C.D. Bloomfield and E.S. Lander

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