famuss

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Functional SNPs Associated with Muscle Size and Strength (FAMuSS)

Description

One goal of the study is to examine the association of demographic, physiological and genetic characteristics with muscle strength. Strength was measured in both dominant and non-dominant arms before and after resistance training. The particular gene of interest here is ACTN3, the "sports gene."

Format

A data frame with 595 observations on the following 9 variables.

ndrm.ch

A numeric vector representing the percent change in strength in a participant's non-dominant arm, from before training and after.

drm.ch

A numeric vector of the percent change in strength in a participant's dominant arm.

sex

A factor with levels Female and Male

age

A numeric vector of participant's age in years.

race

A factor with levels African Am Asian Caucasian Hispanic Other, showing the participant's race.

height

A numeric vector of the participant's height in inches.

weight

A numeric vector of the participant's weight in pounds.

actn3.r577x

A factor with levels CC CT TT, that shows the genotype at residue rs540874 (location r577x) within the ACTN3 gene.

bmi

A numeric vector of the participant's body mass index (bmi).

Details

This data subsets the original data to match as closely as possible the Clarkson 2005 paper. We are off by one or two cases in her dataset.

Source

Data freely available at http://people.umass.edu/foulkes/asg/data.html

Clarkson P, et al., Journal of Applied Physiology 99: 154-163, 2005.

Thompson PD, Moyna M, Seip, R, et al., 2004. Functional Polymorphisms Associated with Human Muscle Size and Strength. Medicine and Science in Sports and Exercise 36:1132 - 1139

References

Pescatello L, et al. Highlights from the functional single nucleotide polymorphisms associated with human muscle size and strength or FAMuSS study, BioMed Research International 2013.

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